Stunning news

new-lymphatic-system-map
Maps of the lymphatic system: old (left) and updated to reflect UVA’s discovery. Image credit: University of Virginia Health System.

This is really, really big news:

In a stunning discovery that overturns decades of textbook teaching, researchers at the University of Virginia School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist. That such vessels could have escaped detection when the lymphatic system has been so thoroughly mapped throughout the body is surprising on its own, but the true significance of the discovery lies in the effects it could have on the study and treatment of neurological diseases ranging from autism to Alzheimer’s disease to multiple sclerosis.

“Instead of asking, ‘How do we study the immune response of the brain?’ ‘Why do multiple sclerosis patients have the immune attacks?’ now we can approach this mechanistically. Because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels,” said Jonathan Kipnis, PhD, professor in the UVA Department of Neuroscience and director of UVA’s Center for Brain Immunology and Glia (BIG). “It changes entirely the way we perceive the neuro-immune interaction. We always perceived it before as something esoteric that can’t be studied. But now we can ask mechanistic questions.”

“We believe that for every neurological disease that has an immune component to it, these vessels may play a major role,” Kipnis said. “Hard to imagine that these vessels would not be involved in a [neurological] disease with an immune component.”

Kevin Lee, PhD, chairman of the UVA Department of Neuroscience, described his reaction to the discovery by Kipnis’ lab: “The first time these guys showed me the basic result, I just said one sentence: ‘They’ll have to change the textbooks.’ There has never been a lymphatic system for the central nervous system, and it was very clear from that first singular observation – and they’ve done many studies since then to bolster the finding – that it will fundamentally change the way people look at the central nervous system’s relationship with the immune system.”

Even Kipnis was skeptical initially. “I really did not believe there are structures in the body that we are not aware of. I thought the body was mapped,” he said. “I thought that these discoveries ended somewhere around the middle of the last century. But apparently they have not.”

So cranial sacral therapists aren’t crazy.

Should psychedelic drugs be legally reclassified?

Purple Haze

When you think of psychedelic drugs, you might imagine a colorful 1960s scene, when LSD and mushrooms were wildly popular among musicians and artists. But scientists have found ways to extract certain compounds from shrooms, acid, and other psychedelics to the benefit of people suffering from depression, anxiety, and even PTSD. A stigma around psychedelic drugs… Continue reading “Should psychedelic drugs be legally reclassified?”

‘99% certain’ pesticides causing health problems

Green the Green/Students Lounging on the Green

Well, there you go! Fortunately, we would never inconvenience American food manufacturers with any socialist restrictions:

Exposure to hormone-disrupting chemicals is likely leading to an increased risk of serious health problems costing at least $175 billion (U.S.) per year in Europe alone, according to a study published Thursday.

Chemicals that can mimic or block estrogen or other hormones are commonly found in thousands of products around the world, including plastics, pesticides, furniture, and cosmetics.

The new research estimated health care costs in Europe, where policymakers are debating whether to enact the world’s first regulations targeting endocrine disruptors. The European Union’s controversial strategy, if approved, would have a profound effect on industries and consumer products worldwide.

Linda Birnbaum, the leading environmental health official in the U.S. government, called the new findings, which include four published papers, “a wake-up call” for policymakers and health experts.

“If you applied these [health care] numbers to the U.S., they would be applicable, and in some cases higher,” says Birnbaum, director of the U.S. National Institute of Environmental Health Sciences.

The researchers detailed the costs related to three types of conditions: neurological effects, such as attention deficit disorders; obesity and diabetes; and male reproductive disorders, including infertility.

Talcum powder and ovarian cancer

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This is a horrifying story. If you’re lucky, there’s no asbestos in your powder — but it might kill you anyway. Fortunately for me, since we grew up poor, we’d put cornstarch in a sock, tie it up and dab ourselves with it when we were hot and sweaty. Hopefully, that won’t kill us!

Suspicions about talc and ovarian cancer go back decades. In 1971, British researchers analyzed 13 ovarian tumors under a microscope and found talc particles ‘’deeply embedded” in 10.

In 1982, the journal Cancer published the first study showing a statistical link between genital talc use and ovarian cancer. Soon after, lead author Dr. Daniel Cramer, a gynecologist and Harvard Medical School professor, was visited by a senior scientist from J&J. He “spent his time trying to convince me that talc use was a harmless habit,” Cramer recalled in a document filed in court, “while I spent my time trying to persuade him … that women should be advised of this potential risk.”

Altogether, about 20 epidemiological studies have found increased rates of ovarian cancer risk for women using talc for hygiene purposes, though some studies have found no association. One report, published by Cramer and several co-authors in 1999, said talc use could be the cause of about 10 percent of ovarian cancers in the U.S.–or some 2,000 cases per year. “Balanced against what are primarily aesthetic reasons for using talc in genital hygiene, the risk benefit decision is not complex,” the study said. “Appropriate warnings should be provided to women about the potential risks of regular use of talc in the genital area.”

In response to such findings, the Cancer Prevention Coalition, an advocacy group, asked the Food and Drug Administration in 1994 to require warnings against talc use for genital hygiene. The agency said it lacked evidence to require warnings, and J&J refused to issue them voluntarily.

Instead, the company and its allies circled the wagons. In 1992, the cosmetic and fragrance association launched a Talc Interested Party Task Force to develop talking points and find experts to rebut studies linking talc to ovarian cancer.

But some statements by the trade group were “inaccurate, to phrase it euphemistically,” a consultant for J&J warned. In two 1997 letters to company officials (here and here), toxicologist Alfred P. Wehner attacked statements that “the scientific evidence did not demonstrate any real association between talc use in consumer products and ovarian tumors.”
Continue reading “Talcum powder and ovarian cancer”

Getting better

anti-inflammatory-foods

I’ve been walking without knee pain for two weeks now. It’s a matter of watching what I eat (and I think the niacinamide still helps, too). As much as I would like to believe that I can eat dairy, bread and rice, it ain’t happening.

At this point, I’m more than happy to make the tradeoff.

Some of the things that changed after I started taking the niacinamide: Tinnitus went away. Ulnar nerve impairment in my left elbow went away. My wrists and fingers don’t hurt all the time. And surprisingly, my mood is much better. It’s an anti-inflammatory, so there’s probably something to the inflammation theory of depression.

Diet Pepsi dropping aspartame

Diet Pepsi Is Dropping The Aspartame — To Include Another Sweetener

Americans love their diet soda, considering they’re consuming 20 percent more than they did just 15 years ago. But after PepsiCo’s diet soda sales dropped 3.2 percent in the first quarter of this year, the company has decided to change up its recipe and swap the artificial sugar additive aspartame for the less controversial sucralose. “This… Continue reading “Diet Pepsi dropping aspartame”

Doing what you love is as Important for your health as exercise

It turns out that not only physical activity will help your mind and body long-term, but so can leisurely activities and hobbies that you truly enjoy. Carving out the time to work in your garden, read books, paint, brew beer, make furniture, knit or sew clothes — whatever your activity of choice — can help you… Continue reading “Doing what you love is as Important for your health as exercise”

News you can use

I'm A Little Tea Pot

One of the weird ADD symptoms I have is constant tightness in my upper back, always. It’s always been that way. I can get a therapeutic massage and on the way home, it’s right back to the status quo. The only time that stopped it was when I used to be on Ritalin (which I can’t take because it was starting to cause Tourette’s symptoms).

But my friend Maya, God bless her, turned me onto passion flower tea. (They call it “the herbal Prozac.”) When she made me try it, I did not believe it would work. But it did. So I don’t care what they call it, this shit works. When I drink it, my neck gets all loose-y goose-y and I feel like I just took a Xanax — which, under the right circumstances, is not such a bad thing.

So if you have a high-stress job, bad relationship, poverty, anger with your elected officials, etc. and want to feel like you took a Xanax, you should try it. Here’s the kind I use.